Cayo Media Luna
- Location: Cuba
- Lat / Lon: N 20° 33.931' / W 077° 53.535'
- Depth: 3 meters
- Tide: 0.3 meters
- Description: Cayo Media Luna is a small nondescript mangrove cayo that offers a decent anchorage very close to the end of the Canal Cuatro Reales. It is a decent place to spend the night during a transit of the Golfo de Guacanayabo. See Waterway Guide Cuba for details on navigation and approaches.
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